Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 2/20 | 0.42 |
| ▸ | ADH1A | P07327 | 2/20 | 0.42 |
| ▸ | ADH7 | P40394 | 2/20 | 0.42 |
| ▸ | ADH1C | P00326 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12643373 | 0.89 | BCHE (0.46) | ADH1BADH1AADH7ADH1CCA12 | |
| SCHEMBL10937119 | 0.82 | CYP2A6 (0.50) | ADH1BADH1AADH7ADH1CKDM4E | |
| SCHEMBL6497592 | 0.81 | ADH1B (0.45) | ADH1BADH1AADH7ADH1CCA12 | |
| SCHEMBL10133724 | 0.79 | KMT2A (0.49) | ADH1BADH1AADH7ADH1CTAAR1 | |
| SCHEMBL22137457 | 0.79 | CA12 (0.44) | CA12CA2CA9BCHETAAR1 | |
| SCHEMBL13358132 | 0.77 | HTT (0.43) | CA12CA2CA9BCHEADRB2 | |
| SCHEMBL19502516 | 0.77 | ALDH1A1 (0.41) | MTNR1AMTNR1BKDM4EMEN1KMT2A | |
| SCHEMBL1268616 | 0.76 | TAAR1 (0.45) | CA12CA2CA9BCHETAAR1 | |
| SCHEMBL22055644 | 0.76 | MEN1 (0.37) | CA12CA2CA9BCHEMTNR1A | |
| SCHEMBL20627277 | 0.76 | TAAR1 (0.35) | ADH1BADH1AADH7ADH1CTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3309146-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALT THEREOF | University of Tsukuba (JP) | 2018-04-18 | — | — | EP | disclosed |