Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.45 |
| ▸ | ADH1C | P00326 | 1/20 | 0.45 |
| ▸ | ADH1A | P07327 | 1/20 | 0.45 |
| ▸ | ADH7 | P40394 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20057564 | 0.81 | ADH1B (0.42) | ADH1BADH1CADH1AADH7CA12 | |
| SCHEMBL6503492 | 0.79 | ADH1B (0.48) | ADH1BADH1CADH1AADH7KMT2A | |
| SCHEMBL12643373 | 0.78 | BCHE (0.46) | ADH1BADH1CADH1AADH7CA12 | |
| SCHEMBL10818547 | 0.74 | ALDH1A1 (0.48) | ADH1BADH1CADH1AADH7KMT2A | |
| SCHEMBL22137457 | 0.73 | CA12 (0.44) | CA12CA2CA9KMT2AMEN1 | |
| SCHEMBL3928290 | 0.72 | CA12 (0.47) | CA12CA2CA9KMT2AMEN1 | |
| SCHEMBL8271347 | 0.72 | MTNR1A (0.58) | CA12CA2CA9HTT | |
| SCHEMBL668864 | 0.71 | ALDH1A1 (0.43) | CA12CA2CA9KMT2AMEN1 | |
| SCHEMBL5638853 | 0.71 | PPIB (0.49) | KMT2AMEN1HTTALDH1A1 | |
| SCHEMBL22482415 | 0.69 | MTNR1A (0.39) | CA12CA2CA9KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | claimed |
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |