Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.58 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | DDX3X | O00571 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | CDK9 | P50750 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16488795 | 0.86 | MEN1 (0.51) | TP53ALDH1A1SAE1UBA2KMT2A | |
| SCHEMBL3460630 | 0.86 | SMN1; SMN2 (0.74) | TP53KMT2AMEN1SIRT1NPC1 | |
| SCHEMBL18311495 | 0.83 | MAPT (0.62) | TP53ALDH1A1SAE1UBA2KMT2A | |
| SCHEMBL13522506 | 0.83 | MEN1 (0.49) | TP53ALDH1A1SAE1UBA2KMT2A | |
| SCHEMBL12711075 | 0.82 | RAB9A (0.77) | TP53ALDH1A1SAE1UBA2KMT2A | |
| SCHEMBL20057679 | 0.82 | DDX3X (0.66) | ALDH1A1KMT2AMEN1SIRT1NPC1 | |
| SCHEMBL17193484 | 0.81 | TP53 (0.81) | TP53KMT2AMEN1SIRT1NPC1 | |
| SCHEMBL17589369 | 0.81 | KMT2A (0.66) | TP53ALDH1A1KMT2AMEN1SIRT1 | |
| SCHEMBL14491938 | 0.81 | SLC2A1 (0.68) | TP53ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL697192 | 0.80 | GPR35 (0.55) | ALDH1A1SAE1UBA2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3309146-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALT THEREOF | University of Tsukuba (JP) | 2018-04-18 | — | — | EP | disclosed |