Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311376 | 0.84 | ALDH1A1 (0.42) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL23577227 | 0.79 | HTT (0.55) | KMT2ASMN1; SMN2 | |
| SCHEMBL29909206 | 0.79 | HTT (0.55) | KMT2ASMN1; SMN2 | |
| SCHEMBL13490015 | 0.79 | KMT2A (0.42) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20313976 | 0.78 | ALDH1A1 (0.50) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8342794 | 0.77 | MEN1 (0.39) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28663316 | 0.77 | ALDH1A1 (0.59) | ALDH1A1LMNAACHE | |
| SCHEMBL19512929 | 0.77 | HSD17B1 (0.55) | MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL27811315 | 0.76 | BRD4 (0.49) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL13490095 | 0.75 | ALDH1A1 (0.42) | MEN1KMT2ASMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3309146-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALT THEREOF | University of Tsukuba (JP) | 2018-04-18 | — | — | EP | disclosed |