Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 4/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.40 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.40 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.39 |
| ▸ | RNASEL | Q05823 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | POLG | P54098 | 1/20 | 0.38 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.37 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20058653 | 0.90 | P2RY1 (0.47) | P2RX1P2RX3P2RX4ENPP1P2RY1 | |
| SCHEMBL16024938 | 0.85 | P2RY1 (0.48) | P2RX1P2RX3P2RX4ENPP1P2RY1 | |
| SCHEMBL23584307 | 0.83 | MGMT (0.40) | — | |
| SCHEMBL20879494 | 0.82 | P2RX3 (0.55) | P2RX1P2RX3P2RX4P2RY1P2RX2 | |
| SCHEMBL22475057 | 0.77 | POLG (0.54) | P2RY6P2RY12POLBPOLG | |
| SCHEMBL19827632 | 0.77 | CA5A (0.44) | P2RX3P2RY1P2RY11RNASEL | |
| SCHEMBL16000595 | 0.76 | P2RY1 (0.42) | P2RX1P2RX3P2RX4ENPP1P2RY1 | |
| SCHEMBL31029199 | 0.76 | P2RY1 (0.68) | P2RX1P2RX3P2RX4ENPP1P2RY1 | |
| SCHEMBL24081936 | 0.76 | NT5E (0.40) | P2RX1P2RX3P2RX4ENPP1P2RY1 | |
| SCHEMBL19187036 | 0.75 | NT5E (0.41) | P2RX1P2RX3P2RX4ENPP1P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906579-B1 | 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION | IDENIX PHARMACEUTICALS LLC (US) | 2018-04-18 | — | — | EP | disclosed |