Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27676406 | 0.98 | MEN1 (0.43) | MEN1KMT2ANPSR1HTTHSD11B1 | |
| SCHEMBL27694967 | 0.86 | MEN1 (0.46) | MEN1KMT2ANPSR1HTTHSD11B1 | |
| SCHEMBL2005913 | 0.80 | HTT (0.38) | MEN1KMT2ANPSR1HTTHSD11B1 | |
| SCHEMBL18582441 | 0.78 | HSD11B1 (0.40) | MEN1KMT2ANPSR1HTTHSD11B1 | |
| SCHEMBL21038138 | 0.75 | MEN1 (0.39) | MEN1KMT2ANPSR1HTTHSD11B1 | |
| SCHEMBL27628848 | 0.74 | HTT (0.40) | MEN1KMT2ANPSR1HTTHSD11B1 | |
| SCHEMBL27676404 | 0.73 | MEN1 (0.40) | MEN1KMT2ANPSR1HTTHSD11B1 | |
| SCHEMBL31253002 | 0.73 | MEN1 (0.40) | MEN1KMT2ANPSR1HTTHSD11B1 | |
| SCHEMBL27869456 | 0.72 | HTT (0.43) | HTTHSD11B1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL21873616 | 0.72 | LMNA (0.37) | MEN1KMT2AHTTHSD11B1GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964758-B2 | Process for production of 2-(substituted phenyl)-3,3,3-trifluoropropene compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-06-21 | — | — | US | disclosed |
| US-20100160683-A1 | Process for Production of 2-(Substituted Phenyl)-3,3,3-Trifluoropropene Compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160683-A1 | Process for Production of 2-(Substituted Phenyl)-3,3,3-Trifluoropropene Compound | PEX3, SCO2, LPO | MEN1 1622/4885KMT2A 2764/4885NPSR1 3250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.