SCHEMBL2005985

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2008819	0.90	NAAA (0.41)	TRPV1CHRM4ATMSMN1; SMN2KIT
	SCHEMBL2006228	0.89	FAAH (0.47)	TRPV1CHRM4LMNAKITCNR1
	SCHEMBL27729524	0.89	CNR1 (0.39)	TRPV1CHRM4KITCNR1
	SCHEMBL2006222	0.88	KDM4E (0.47)	TRPV1CHRM4LMNAPOLBKIT
	SCHEMBL2005538	0.85	GAA (0.52)	TRPV1GAALMNATP53POLB
	SCHEMBL2008277	0.85	CHRM4 (0.41)	TRPV1CHRM2CHRM1CHRM4MAPT
	SCHEMBL2007919	0.83	CNR1 (0.48)	TRPV1CHRM2CHRM1CHRM4LMNA
	SCHEMBL2008496	0.83	CNR1 (0.43)	TRPV1CHRM2CHRM1TP53POLB
	SCHEMBL3143748	0.82	FAAH (0.58)	TRPV1GAALMNATP53POLB
	SCHEMBL2009642	0.82	TRPV1 (0.46)	TRPV1CHRM2CHRM1CHRM4KIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.