Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.43 |
| ▸ | TUBB | P07437 | 3/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20061660 | 0.90 | HTR3A (0.42) | HTR3AHRH4KDM4ETUBB4ATUBB | |
| SCHEMBL1308852 | 0.80 | KDM4E (0.53) | HTR3AHRH4KDM4ETUBB4ATUBB | |
| SCHEMBL13343598 | 0.73 | KDM4E (0.57) | HTR3AHRH4KDM4ETUBB4ATUBB | |
| SCHEMBL689649 | 0.70 | ALDH1A1 (0.53) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL31317497 | 0.68 | TOP2A (0.54) | HTR3AHRH4KDM4ETUBB4ATUBB | |
| SCHEMBL31463101 | 0.67 | TYMS (0.72) | HTR3AHRH4KDM4ETUBB4ATUBB | |
| SCHEMBL5313776 | 0.67 | TYMS (0.72) | HTR3AHRH4KDM4ETUBB4ATUBB | |
| SCHEMBL3423481 | 0.67 | KDM4E (0.59) | HTR3AHRH4KDM4ETUBB4ATUBB | |
| SCHEMBL17298011 | 0.67 | TUBB4A (0.66) | HTR3AHRH4KDM4ETUBB4ATUBB | |
| SCHEMBL6928482 | 0.65 | TUBB4A (0.68) | HTR3AHRH4KDM4ETUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069470-A1 | NEW COMPOUNDS AND USES THEREOF FOR DETECTION OF TARGET MOLECULES IN A SAMPLE | UNIVERSITE DE GENEVE (CH) | 2018-04-19 | — | — | WO | disclosed |