SCHEMBL20061808

SCHEMBL20061808

c1ccc2c(c1)C1c3ccncc3C2c2cc3cocc3cc21

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
HTT P42858 1/20 0.33
RAD52 P43351 1/20 0.33
CLK1 P49759 1/20 0.33
CYP2A6 P11509 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 1/20 0.32
PRKCZ Q05513 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20061801 0.86 CYP17A1 (0.38) KDM4EPOLBHTTRAD52CLK1
SCHEMBL20061813 0.84 CYP2A6 (0.31) CLK1CYP2A6
SCHEMBL20061825 0.84 MEN1 (0.34) KDM4ECYP3A4ALDH1A1PKMHPGD
SCHEMBL20061820 0.82 EGFR (0.30)
SCHEMBL20061785 0.82 L3MBTL1 (0.38) KDM4EPOLBHTTRAD52CYP2A6
SCHEMBL20061810 0.80 KDM4E (0.33) KDM4EPOLBHTTRAD52ALDH1A1
SCHEMBL20061804 0.78 EGFR (0.35) KDM4E
SCHEMBL20061802 0.76 NPC1 (0.30) NPC1ALDH1A1
SCHEMBL20061798 0.75 APAF1 (0.32) HTTALDH1A1HPGD
SCHEMBL20061790 0.73 PDPK1 (0.35) KDM4EPOLBHTTRAD52CLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11239432-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-02-01 US disclosed
US-20180108848-A1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-04-19 US disclosed
US-20180108848-A1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11239432-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 KDM4E 4450/4885POLB 2476/4885HTT 4366/4885
US-20180108848-A1 Organic electroluminescent materials and devices OSBP, OSBP2, OCIAD2 KDM4E 4668/4885POLB 1972/4885HTT 3968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.