Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 4/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.41 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5386792 | 0.83 | L3MBTL1 (0.65) | L3MBTL1GLAPOLBSMN1; SMN2KDM4E | |
| SCHEMBL266662 | 0.80 | L3MBTL1 (0.72) | L3MBTL1GLAPOLBSMN1; SMN2KDM4E | |
| SCHEMBL4669737 | 0.78 | L3MBTL1 (0.65) | L3MBTL1GLAPOLBSMN1; SMN2KDM4E | |
| SCHEMBL7402587 | 0.76 | KDM4E (0.61) | L3MBTL1GLAPOLBSMN1; SMN2KDM4E | |
| SCHEMBL7169786 | 0.74 | KDM4E (0.58) | L3MBTL1GLAPOLBSMN1; SMN2KDM4E | |
| SCHEMBL9545380 | 0.74 | KMT2A (0.58) | L3MBTL1GLAPOLBSMN1; SMN2KDM4E | |
| SCHEMBL28148536 | 0.74 | TSHR (0.60) | L3MBTL1GLALTB4R | |
| SCHEMBL5317677 | 0.73 | GABRA1 (0.56) | L3MBTL1TDP1 | |
| SCHEMBL12015669 | 0.72 | L3MBTL1 (0.54) | L3MBTL1GLAPOLBSMN1; SMN2KDM4E | |
| SCHEMBL4576444 | 0.72 | L3MBTL1 (0.66) | L3MBTL1GLAPOLBSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088926-B2 | Substituted 2-methyl-2-phenoxy-N-propyl-propionamides as cannabinoid receptor antagonists/inverse agonists useful for treating obesity | JENRIN DISCOVERY, INC. (US) | 2012-01-03 | — | — | US | disclosed |