SCHEMBL20062879

SCHEMBL20062879

CC(C)(C)c1ccc2c(c1)N(c1cccc(-c3ccccc3)n1)/C(=C1\N(c3cccc(-c4ccccc4)n3)c3ccc(C(C)(C)C)cc3N1c1cccc(-c3ccccc3)n1)N2c1cccc(-c2ccccc2)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
RAB9A P51151 2/20 0.39
KIF11 P52732 1/20 0.37
COMT P21964 1/20 0.35
MAPT P10636 2/20 0.34
POLB P06746 1/20 0.34
ASIC3 Q9UHC3 1/20 0.34
ADORA3 P0DMS8 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
NPSR1 Q6W5P4 2/20 0.34
XBP1 P17861 1/20 0.34
KEAP1 Q14145 1/20 0.34
NFE2L2 Q16236 1/20 0.34
LMNA P02545 2/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
NR1H3 Q13133 1/20 0.33
CCR4 P51679 1/20 0.32
METAP2 P50579 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20681879 0.82 MEN1 (0.39) MEN1KMT2ARAB9AKIF11COMT
SCHEMBL20062886 0.81 NR1H3 (0.33) KIF11NR1H3
SCHEMBL20062898 0.75 CHRNB2 (0.40) MEN1KMT2AMAPTPOLBNPSR1
SCHEMBL18905680 0.74 TSHR (0.38) RAB9AKIF11MAPTPOLBLMNA
SCHEMBL18905689 0.74 TSHR (0.38) RAB9AKIF11MAPTPOLBLMNA
SCHEMBL19343033 0.72 HRH3 (0.36) MEN1KMT2A
SCHEMBL20062960 0.72 AR (0.38) RAB9AKIF11NR1H3NPC1RXRA
SCHEMBL27984694 0.71 RAB9A (0.64) MEN1KMT2ARAB9AKIF11MAPT
SCHEMBL23196598 0.71 MEN1 (0.39) MEN1KMT2ARAB9AKIF11COMT
SCHEMBL20062888 0.71 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed