SCHEMBL20062880

SCHEMBL20062880

Cc1cc2c(cc1C)N(c1cccc(C(C)(C)C)n1)C(=C1N(c3cccc(C(C)(C)C)n3)c3cc(C)c(C)cc3N1c1cccc(C(C)(C)C)n1)N2c1cccc(C(C)(C)C)n1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35
RECQL P46063 1/20 0.33
GRIN2B Q13224 1/20 0.32
IRAK4 Q9NWZ3 1/20 0.31
MAPK13 O15264 1/20 0.31
MAPK12 P53778 1/20 0.31
MAPK11 Q15759 1/20 0.31
MAPK14 Q16539 1/20 0.31
CCR4 P51679 2/20 0.31
MAPT P10636 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30
RAB9A P51151 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062886 0.83 NR1H3 (0.33)
SCHEMBL20062881 0.80 RECQL (0.51) RECQLGRIN2BIRAK4MAPTKDM4E
SCHEMBL20681852 0.79 GAA (0.32) GAAHPGDGRIN2BIRAK4MAPK13
SCHEMBL20062930 0.73 HSD17B10 (0.33) GAAHPGDKDM4EALDH1A1LMNA
SCHEMBL20062916 0.73 GAA (0.35) GAAHPGDKDM4EALDH1A1LMNA
SCHEMBL10068138 0.70 ALDH1A1 (0.45) GAAHPGDRECQLMAPTKDM4E
SCHEMBL18199843 0.69 SMN1; SMN2 (0.55) GAAHPGDGRIN2BMAPK14MAPT
SCHEMBL19343029 0.69 ALDH1A1 (0.50) GAAMAPTKDM4EALDH1A1RAB9A
SCHEMBL20062896 0.68 ELANE (0.33) GAAHPGDMAPK13MAPK12MAPK11
SCHEMBL42955 0.67 PGK1 (0.39) GAAHPGDCCR4KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same CANON KABUSHIKI KAISHA (JP) 2019-01-29 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same BRD1, DRD1, NR2E3 GAA 4583/4885HPGD 3728/4885RECQL 1643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.