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Sugi Predict / Compounds / SCHEMBL20062897

SCHEMBL20062897

SCHEMBL20062897

CC(C)(C)c1cncc(N2C(=C3N(c4cncc(C(C)(C)C)c4)c4ccccc4N3c3cncc(C(C)(C)C)c3)N(c3cncc(C(C)(C)C)c3)c3ccccc32)c1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CYP11B2 P19099 20/20 0.40
▸ CYP11B1 P15538 17/20 0.40
▸ CYP19A1 P11511 5/20 0.36
▸ CYP2C9 P11712 5/20 0.36
▸ CYP3A4 P08684 1/20 0.33
▸ CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18905645 0.80 GABRA1 (0.37) —
SCHEMBL18905720 0.77 HDAC4 (0.42) —
SCHEMBL18905676 0.74 PMM2 (0.40) —
SCHEMBL20062895 0.72 ALDH1A1 (0.44) CYP19A1CYP3A4
SCHEMBL21848986 0.72 CYP11B2 (0.38) CYP11B2CYP11B1CYP19A1CYP2C9CYP3A4
SCHEMBL20062915 0.70 HPGD (0.38) —
SCHEMBL20062933 0.70 ATM (0.39) —
SCHEMBL19343008 0.70 HSP90AA1 (0.39) CYP2C9
SCHEMBL18905680 0.69 TSHR (0.38) CYP2D6
SCHEMBL18905689 0.69 TSHR (0.38) CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 — — US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 — — US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 — — US disclosed