SCHEMBL20062901

SCHEMBL20062901

Fc1ccc(N2C(=C3N(c4ccc(F)nc4)c4ccccc4N3c3ccc(F)nc3)N(c3ccc(F)nc3)c3ccccc32)cn1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.40
CHRNA4 P43681 1/20 0.40
HSD17B3 P37058 1/20 0.33
ELOVL1 Q9BW60 1/20 0.32
DPP4 P27487 1/20 0.32
DPP8 Q6V1X1 1/20 0.32
DPP9 Q86TI2 1/20 0.32
DPP7 Q9UHL4 1/20 0.32
CYP2E1 P05181 1/20 0.31
CYP2A6 P11509 1/20 0.31
CYP2B6 P20813 1/20 0.31
DRD2 P14416 1/20 0.31
DRD4 P21917 1/20 0.31
DRD3 P35462 1/20 0.31
TLR9 Q9NR96 1/20 0.30
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30
CCR9 P51686 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17383346 0.73 MGLL (0.46) TLR9
SCHEMBL19343026 0.68 NPC1 (0.39) CYP2A6CYP11B1CYP11B2
SCHEMBL20062887 0.68 HTT (0.56) CHRNB2CHRNA4CYP2E1CYP2A6CYP11B2
SCHEMBL20062933 0.67 ATM (0.39) CYP2A6TLR9
SCHEMBL25184171 0.67 KMT2A (0.50) CHRNB2CHRNA4HSD17B3CCR9
SCHEMBL27252424 0.67 F10 (0.40) CHRNB2CHRNA4ELOVL1
SCHEMBL17383504 0.67 ALDH1A1 (0.46) TLR9
SCHEMBL20062899 0.66 ELANE (0.44) CHRNB2CHRNA4HSD17B3
SCHEMBL19343023 0.65 CYP1A2 (0.34) TLR9
SCHEMBL29582723 0.65 NR3C1 (0.46) CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed