SCHEMBL20062945

SCHEMBL20062945

Cc1nc(C)nc(N2C(=C3N(c4nc(C)nc(C)n4)c4cc(C)c(C)cc4N3c3nc(C)nc(C)n3)N(c3nc(C)nc(C)n3)c3cc(C)c(C)cc32)n1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062930 0.76 HSD17B10 (0.33)
SCHEMBL20062946 0.76 HRH4 (0.30)
SCHEMBL20062921 0.74 KDM4E (0.33)
SCHEMBL20072006 0.74 HTT (0.34) HTT
SCHEMBL20681871 0.70 TSHR (0.33)
SCHEMBL20062889 0.67 CCR1 (0.33)
SCHEMBL18905744 0.67 MGLL (0.52) HTT
SCHEMBL20062924 0.64 ALDH1A1 (0.39) HTT
SCHEMBL20062881 0.64 RECQL (0.51)
SCHEMBL20062916 0.64 GAA (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed