SCHEMBL20062935

SCHEMBL20062935

c1ccc2c(c1)N(c1cnccn1)C(=C1N(c3cnccn3)c3ccccc3N1c1cnccn1)N2c1cnccn1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
LMNA P02545 1/20 0.46
SLC6A7 Q99884 1/20 0.36
POLB P06746 1/20 0.36
ALOX15 P16050 1/20 0.36
NR4A1 P22736 1/20 0.36
P4HTM Q9NXG6 1/20 0.36
SCN9A Q15858 1/20 0.35
SORD Q00796 1/20 0.34
ALDH1A1 P00352 3/20 0.34
CYP17A1 P05093 2/20 0.34
CYP1A2 P05177 2/20 0.34
KDM4E B2RXH2 2/20 0.34
DRD4 P21917 1/20 0.34
MEN1 O00255 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
TP53 P04637 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
HSP90AA1 P07900 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062878 0.77 SMN1; SMN2 (0.53) LMNAPOLBP4HTMALDH1A1CYP1A2
SCHEMBL20072041 0.74 L3MBTL1 (0.45) L3MBTL1LMNASLC6A7POLBALOX15
SCHEMBL20062939 0.73 RPS6KA5 (0.42) SORDCYP17A1CYP1A2DRD4SMN1; SMN2
SCHEMBL5616510 0.73 HTT (0.56) LMNAPOLBP4HTMALDH1A1KDM4E
SCHEMBL27481595 0.73 HPGD (0.53) L3MBTL1LMNASLC6A7POLBALOX15
SCHEMBL20062887 0.69 HTT (0.56) L3MBTL1ALDH1A1
SCHEMBL17335801 0.68 ROCK1 (0.57) L3MBTL1LMNAPOLBALOX15NR4A1
SCHEMBL12929419 0.68 L3MBTL1 (0.47) L3MBTL1LMNASLC6A7POLBALOX15
SCHEMBL1273451 0.68 L3MBTL1 (0.43) L3MBTL1LMNASLC6A7POLBALOX15
SCHEMBL14799995 0.68 KDM4E (0.43) L3MBTL1LMNASLC6A7POLBP4HTM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed