SCHEMBL14799995

SCHEMBL14799995

c1ccc2nn(-c3cnccn3)nc2c1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.43
HPGD P15428 1/20 0.43
LMNA P02545 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SORD Q00796 1/20 0.41
SLC6A7 Q99884 1/20 0.39
METAP2 P50579 1/20 0.38
ALDH1A1 P00352 1/20 0.37
DRD4 P21917 1/20 0.37
P4HTM Q9NXG6 1/20 0.36
DUSP4 Q13115 1/20 0.35
PTP4A1 Q93096 1/20 0.35
HTT P42858 1/20 0.35
MAPT P10636 1/20 0.35
ACHE P22303 1/20 0.35
POLB P06746 1/20 0.34
CYP17A1 P05093 1/20 0.34
CYP1A2 P05177 1/20 0.34
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12075261 0.77 POLB (0.50) KDM4EHPGDSORDALDH1A1MAPT
SCHEMBL14799965 0.73 SORD (0.36) KDM4ELMNAL3MBTL1SORDSLC6A7
SCHEMBL9989822 0.73 METAP2 (0.36) LMNAL3MBTL1SORDSLC6A7METAP2
SCHEMBL15333133 0.71 POLB (0.67) HTTMAPTPOLBCYP17A1CYP1A2
SCHEMBL20062935 0.68 L3MBTL1 (0.46) KDM4EHPGDLMNAL3MBTL1SORD
SCHEMBL12075546 0.67 KDM4E (0.52) KDM4EHPGDLMNAL3MBTL1ALDH1A1
SCHEMBL20072041 0.67 L3MBTL1 (0.45) KDM4ELMNAL3MBTL1SORDSLC6A7
SCHEMBL16484365 0.67 L3MBTL1 (0.42) KDM4ELMNAL3MBTL1ACHECYP17A1
SCHEMBL14799765 0.66 KDM4E (0.70) KDM4EHPGDLMNAALDH1A1HTT
SCHEMBL977966 0.66 HSP90AA1 (0.37) KDM4ELMNAL3MBTL1SORDSLC6A7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9382424-B2 Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-05 US disclosed
US-9382424-B2 Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-05 US disclosed
US-9382424-B2 Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-05 US disclosed
WO-2013049062-A2 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-04-04 WO disclosed
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-03-28 US disclosed
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-03-28 US disclosed
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY SUN2, NES, CRY1 KDM4E 983/4885HPGD 1452/4885LMNA 792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.