SCHEMBL20072041

SCHEMBL20072041

c1ccc2c(c1)N(c1cnccn1)C(C1N(c3cnccn3)c3ccccc3N1c1cnccn1)N2c1cnccn1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.45
LMNA P02545 1/20 0.45
SLC6A7 Q99884 1/20 0.35
POLB P06746 1/20 0.35
ALOX15 P16050 1/20 0.35
NR4A1 P22736 1/20 0.35
P4HTM Q9NXG6 1/20 0.35
KDM4E B2RXH2 3/20 0.35
TP53 P04637 1/20 0.35
SCN9A Q15858 1/20 0.34
SORD Q00796 1/20 0.33
THRB P10828 1/20 0.33
ALDH1A1 P00352 1/20 0.33
DRD4 P21917 1/20 0.33
METAP2 P50579 1/20 0.33
CYP17A1 P05093 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20681919 0.78 EP300 (0.44) LMNAPOLBP4HTMKDM4EALDH1A1
SCHEMBL20062935 0.74 L3MBTL1 (0.46) L3MBTL1LMNASLC6A7POLBALOX15
SCHEMBL18193035 0.71 HTT (0.46) L3MBTL1
SCHEMBL20681830 0.70 GAA (0.42) LMNAPOLBP4HTMKDM4EALDH1A1
SCHEMBL12929419 0.67 L3MBTL1 (0.47) L3MBTL1LMNASLC6A7POLBALOX15
SCHEMBL1273451 0.67 L3MBTL1 (0.43) L3MBTL1LMNASLC6A7POLBALOX15
SCHEMBL17335801 0.67 ROCK1 (0.57) L3MBTL1LMNAPOLBALOX15NR4A1
SCHEMBL20681874 0.67 LMNA (0.39) LMNAKDM4EALDH1A1
SCHEMBL20071990 0.67 ROCK1 (0.42) LMNAKDM4ECYP17A1
SCHEMBL14799995 0.67 KDM4E (0.43) L3MBTL1LMNASLC6A7POLBP4HTM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same CANON KABUSHIKI KAISHA (JP) 2019-01-29 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same BRD1, DRD1, NR2E3 L3MBTL1 498/4885LMNA 4611/4885SLC6A7 4237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.