SCHEMBL20072006

SCHEMBL20072006

Cc1nc(C)nc(N2c3cc(C)c(C)cc3N(c3nc(C)nc(C)n3)C2C2N(c3nc(C)nc(C)n3)c3cc(C)c(C)cc3N2c2nc(C)nc(C)n2)n1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.34
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062945 0.74 HTT (0.34) HTT
SCHEMBL20681865 0.71 NOS3 (0.30)
SCHEMBL20681862 0.68 DPP4 (0.33) HTTKDM4EMAPT
SCHEMBL20681917 0.67 HTR3E (0.42) KDM4EMAPT
SCHEMBL20681886 0.67 NOS3 (0.35)
SCHEMBL20071970 0.67 ADRB2 (0.34) KDM4EMAPT
SCHEMBL18911915 0.67 HSP90AA1 (0.35) KDM4EMAPT
SCHEMBL18911919 0.67 ADRB1 (0.31)
SCHEMBL18911912 0.65 RAB9A (0.44) HTTKDM4EMAPT
SCHEMBL20072096 0.64 KDM4E (0.42) HTTKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed