SCHEMBL20062955

SCHEMBL20062955

Cc1cc2c(cc1C)N(c1ccc(-c3ccccc3)o1)C(=C1N(c3ccc(-c4ccccc4)o3)c3cc(C)c(C)cc3N1c1ccc(-c3ccccc3)o1)N2c1ccc(-c2ccccc2)o1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.38
MAOA P21397 1/20 0.38
KMT2A Q03164 1/20 0.38
HPGD P15428 2/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
PDE4B Q07343 2/20 0.36
S1PR4 O95977 1/20 0.35
CYP2E1 P05181 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2A6 P11509 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2B6 P20813 1/20 0.35
CYP2C19 P33261 1/20 0.35
NQO2 P16083 1/20 0.34
HRH1 P35367 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PRKDC P78527 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062958 0.80 PRKDC (0.34) KMT2AHPGDCYP2E1CYP3A4CYP2D6
SCHEMBL20071966 0.79 MAOB (0.37) MAOBMAOAKMT2AHPGDLMNA
SCHEMBL18905741 0.70 FAAH (0.46) KMT2AMAPTALDH1A1
SCHEMBL17383518 0.69 NPC1 (0.45) KMT2AHPGDMAPTNPSR1CYP2C19
SCHEMBL18905754 0.68 ALDH1A1 (0.51) MAPTCYP2D6ALDH1A1
SCHEMBL18905756 0.66 NPC1 (0.42) KMT2AHPGDLMNAMAPTNPSR1
SCHEMBL20062919 0.66 KMT2A (0.45) KMT2AHPGDMAPTNPSR1ALDH1A1
SCHEMBL18905744 0.65 MGLL (0.52) KMT2AHPGDMAPTNQO2ALDH1A1
SCHEMBL76097 0.65 CYP2E1 (0.58) KMT2AHPGDLMNAMAPTCYP2E1
SCHEMBL2199459 0.64 PTGS1 (0.55) MAOBMAOAKMT2AHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same CANON KABUSHIKI KAISHA (JP) 2019-01-29 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same BRD1, DRD1, NR2E3 MAOB 1529/4885MAOA 2469/4885KMT2A 2024/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.