SCHEMBL20071966

SCHEMBL20071966

Cc1cc2c(cc1C)N(c1ccc(-c3ccccc3)o1)C(C1N(c3ccc(-c4ccccc4)o3)c3cc(C)c(C)cc3N1c1ccc(-c3ccccc3)o1)N2c1ccc(-c2ccccc2)o1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.37
MAOA P21397 1/20 0.37
KMT2A Q03164 1/20 0.37
HPGD P15428 2/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
PDE4B Q07343 1/20 0.35
GFER P55789 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
S1PR4 O95977 1/20 0.35
CYP2E1 P05181 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2A6 P11509 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2B6 P20813 1/20 0.34
CYP2C19 P33261 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20071967 0.81 HPGD (0.34) KMT2AHPGDGFERSMN1; SMN2CYP2E1
SCHEMBL20062955 0.79 MAOB (0.38) MAOBMAOAKMT2AHPGDLMNA
SCHEMBL18911785 0.71 FAAH (0.36) MAPT
SCHEMBL18911912 0.70 RAB9A (0.44) HPGDLMNAMAPTSMN1; SMN2CYP2C19
SCHEMBL18911788 0.69 HTR7 (0.44) MAPTSMN1; SMN2CYP3A4CYP2D6
SCHEMBL20071976 0.67 NPC1 (0.41) KMT2AHPGDLMNAMAPTCYP2C19
SCHEMBL20681832 0.67 MAPT (0.44) KMT2AHPGDMAPTNPSR1SMN1; SMN2
SCHEMBL18911715 0.66 ADRB1 (0.42) KMT2AHPGDLMNAMAPTNPSR1
SCHEMBL76097 0.64 CYP2E1 (0.58) KMT2AHPGDLMNAMAPTGFER
SCHEMBL18911717 0.64 ALDH1A1 (0.38) HPGDLMNAMAPTNPSR1GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed