Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 8/20 | 0.40 |
| ▸ | LPAR4 | Q99677 | 4/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20063070 | 1.00 | USP2 (0.71) | USP2CYP3A4MAPTSMN1; SMN2LMNA | |
| SCHEMBL20063076 | 0.95 | USP2 (0.79) | USP2CYP3A4MAPTSMN1; SMN2LMNA | |
| Dehydroavocatin-1-Acetate SCHEMBL12998512 | 0.83 | MAPT (1.00) | USP2CYP3A4MAPTSMN1; SMN2LMNA | |
| Avocatin A SCHEMBL31368575 | 0.76 | USP2 (1.00) | USP2CYP3A4MAPTSMN1; SMN2LMNA | |
| Avocatin A SCHEMBL10060809 | 0.76 | USP2 (1.00) | USP2CYP3A4MAPTSMN1; SMN2LMNA | |
| Avocatin A SCHEMBL898834 | 0.76 | USP2 (1.00) | USP2CYP3A4MAPTSMN1; SMN2LMNA | |
| SCHEMBL1164200 | 0.72 | USP2 (0.63) | USP2CYP3A4MAPTSMN1; SMN2LMNA | |
| SCHEMBL15944389 | 0.72 | USP2 (0.75) | USP2CYP3A4MAPTSMN1; SMN2LMNA | |
| SCHEMBL4948952 | 0.71 | USP2 (0.70) | USP2CYP3A4MAPTSMN1; SMN2LMNA | |
| Undecylenic Acid SCHEMBL28809242 | 0.70 | MAPT (0.62) | USP2CYP3A4MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180103671-A1 | INHIBITORY ACTIVITY OF ACETOGENINS AGAINST LISTERIA MONOCYTOGENES | INSTITUTO TECNOLOGICO Y DE ESTUDIOS SUPERIORES DE MONTERREY (MX) | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180103671-A1 | INHIBITORY ACTIVITY OF ACETOGENINS AGAINST LISTERIA MONOCYTOGENES | LTN1, LCT, LSS | USP2 1358/4885CYP3A4 4070/4885MAPT 3556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.