Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | PKM | P14618 | 4/20 | 0.64 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8460899 | 0.89 | PKM (0.64) | SMN1; SMN2NPC1RAB9APKMNR1H4 | |
| SCHEMBL8460896 | 0.86 | ALDH1A1 (0.53) | SMN1; SMN2NPC1RAB9APKMNR1H4 | |
| SCHEMBL5027170 | 0.85 | MAPT (0.58) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9453202 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9APKMNR1H4 | |
| SCHEMBL20064060 | 0.81 | RAB9A (0.62) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL25950796 | 0.80 | RARA (0.53) | SMN1; SMN2RAB9ANR1H4MEN1KMT2A | |
| SCHEMBL8442730 | 0.79 | NR1H4 (0.53) | SMN1; SMN2NPC1RAB9ANR1H4MEN1 | |
| SCHEMBL4611487 | 0.78 | HDAC3 (0.71) | SMN1; SMN2NPC1RAB9ANR1H4MEN1 | |
| SCHEMBL3882727 | 0.78 | HDAC3 (0.71) | SMN1; SMN2NPC1RAB9ANR1H4MEN1 | |
| SCHEMBL7301440 | 0.78 | SMN1; SMN2 (0.78) | SMN1; SMN2NPC1RAB9APKMNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232199-B1 | AROMATIC BENZAMIDO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AS WELL AS IN COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1993-02-03 | — | — | EP | claimed |