SCHEMBL2006563

SCHEMBL2006563

c1c[nH]c([Ru]c2ccc[nH]2)c1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
AURKA O14965 1/20 0.35
AURKB Q96GD4 1/20 0.35
INCENP Q9NQS7 1/20 0.35
FKBP5 Q13451 1/20 0.33
TSHR P16473 1/20 0.32
MCL1 Q07820 1/20 0.31
NAPRT Q6XQN6 1/20 0.31
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3341591 0.77
SCHEMBL3338440 0.77
SCHEMBL4024392 0.75 ADRA1A (0.38)
SCHEMBL3336643 0.75
SCHEMBL3341201 0.72 AHR (0.31)
SCHEMBL2005078 0.72
SCHEMBL3337052 0.72 ATM (0.31)
SCHEMBL3338350 0.72
SCHEMBL3339721 0.71
SCHEMBL3344261 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1814892-B1 ORGANOMETALLIC COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF PRAXAIR TECHNOLOGY INC (US) 2013-12-11 EP claimed
US-20090203917-A1 ORGANOMETALLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND METHODS OF USE THEREOF PRAXAIR TECHNOLOGY, INC. 2009-08-13 US claimed
WO-2009094259-A1 ORGANOMETALLIC COMPOUNDS PROCESSES AND METHODS OF USE PRAXAIR TECHNOLOGY, INC. (US) 2009-07-30 WO claimed
EP-1814892-A2 ORGANOMETALLIC COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF PRAXAIR TECHNOLOGY, INC. (US) 2007-08-08 EP claimed
US-20070054487-A1 ATOMIC LAYER DEPOSITION PROCESSES FOR RUTHENIUM MATERIALS APPLIED MATERIALS, INC. 2007-03-08 US claimed
WO-2006044446-A2 ORGANOMETALLIC COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF PRAXAIR TECHNOLOGY, INC. (US) 2006-04-27 WO claimed
US-20060083857-A1 Organometallic compounds and processes for preparation thereof PRAXAIR TECHNOLOGY, INC. 2006-04-20 US claimed
US-9418890-B2 Method for tuning a deposition rate during an atomic layer deposition process APPLIED MATERIALS, INC. (US) 2016-08-16 US disclosed
US-9032906-B2 Apparatus and process for plasma-enhanced atomic layer deposition APPLIED MATERIALS, INC. (US) 2015-05-19 US disclosed
US-20140248772-A1 METHOD FOR TUNING A DEPOSITION RATE DURING AN ATOMIC LAYER DEPOSITION PROCESS APPLIED MATERIALS, INC. (US) 2014-09-04 US disclosed
EP-1814892-B1 ORGANOMETALLIC COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF PRAXAIR TECHNOLOGY INC (US) 2013-12-11 EP disclosed
US-8491967-B2 In-situ chamber treatment and deposition process APPLIED MATERIALS, INC. (US) 2013-07-23 US disclosed
US-8221837-B2 Organometallic compounds and processes for preparation thereof PRAXAIR TECHNOLOGY, INC. (US) 2012-07-17 US disclosed
US-20070128864-A1 APPARATUS AND PROCESS FOR PLASMA-ENHANCED ATOMIC LAYER DEPOSITION APPLIED MATERIALS, INC. 2007-06-07 US disclosed
US-20070119370-A1 APPARATUS AND PROCESS FOR PLASMA-ENHANCED ATOMIC LAYER DEPOSITION APPLIED MATERIALS, INC. 2007-05-31 US disclosed
US-20070119371-A1 APPARATUS AND PROCESS FOR PLASMA-ENHANCED ATOMIC LAYER DEPOSITION APPLIED MATERIALS, INC. 2007-05-31 US disclosed
US-20070077750-A1 ATOMIC LAYER DEPOSITION PROCESSES FOR RUTHENIUM MATERIALS APPLIED MATERIALS, INC. 2007-04-05 US disclosed
US-20070054487-A1 ATOMIC LAYER DEPOSITION PROCESSES FOR RUTHENIUM MATERIALS APPLIED MATERIALS, INC. 2007-03-08 US disclosed
WO-2006044446-A2 ORGANOMETALLIC COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF PRAXAIR TECHNOLOGY, INC. (US) 2006-04-27 WO disclosed
US-20060083857-A1 Organometallic compounds and processes for preparation thereof PRAXAIR TECHNOLOGY, INC. 2006-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060083857-A1 Organometallic compounds and processes for preparation thereof TLL2, LOXL2, EML4 DAO 2007/4885HDAC8 4839/4885HDAC6 4590/4885
US-20090203917-A1 ORGANOMETALLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND METHODS OF USE THEREOF L1CAM, TLL2, LANCL2 DAO 3198/4885HDAC8 4810/4885HDAC6 4537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.