Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 3/20 | 0.35 |
| ▸ | CDK8 | P49336 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | ITK | Q08881 | 1/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.32 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.32 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133997 | 0.80 | LMNA (0.50) | CCNCCDK8KMT2AMEN1HDAC1 | |
| SCHEMBL20221453 | 0.74 | MAPT (0.39) | CCNCCDK8HDAC1HDAC6ERN1 | |
| SCHEMBL20120111 | 0.73 | SMN1; SMN2 (0.40) | KMT2AMEN1LTA4HSMN1; SMN2 | |
| SCHEMBL12786457 | 0.73 | SMN1; SMN2 (0.40) | KMT2AMEN1LTA4HSMN1; SMN2 | |
| SCHEMBL19774539 | 0.72 | LMNA (0.33) | CCNCCDK8ERN1LMNAMAPT | |
| SCHEMBL12071049 | 0.71 | KMO (0.51) | MEN1ERN1LMNASMN1; SMN2MAPT | |
| SCHEMBL10028645 | 0.69 | KMO (0.57) | HDAC1LMNASMN1; SMN2MAPT | |
| SCHEMBL5924950 | 0.68 | NAPRT (0.60) | CCNCCDK8HDAC1HDAC6CDC7 | |
| SCHEMBL14243405 | 0.68 | TPMT (0.43) | LMNASMN1; SMN2MAPT | |
| SCHEMBL17089053 | 0.68 | NAPRT (0.60) | CCNCCDK8HDAC1HDAC6CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3526227-B1 | BINUCLEAR METAL COMPLEXES AND ELECTRONIC DEVICES, IN PARTICULAR ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING SAID METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2020-06-03 | — | — | EP | disclosed |
| WO-2018069196-A1 | BINUCLEAR METAL COMPLEXES AND ELECTRONIC DEVICES, IN PARTICULAR ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING SAID METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2018-04-19 | — | — | WO | disclosed |