Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20069061 | 0.86 | DPP4 (0.36) | DPP4CYP1A2TDP1ALDH1A1KDM4E | |
| SCHEMBL20069051 | 0.85 | DPP4 (0.32) | XIAPDPP4 | |
| SCHEMBL20070121 | 0.81 | ALDH1A1 (0.33) | DPP4ALDH1A1 | |
| SCHEMBL20069554 | 0.77 | CYP1A2 (0.37) | CYP1A2TDP1ALDH1A1 | |
| SCHEMBL20069553 | 0.70 | DPP4 (0.33) | DPP4KDM4E | |
| SCHEMBL25590181 | 0.70 | ALDH1A1 (0.32) | ALDH1A1KDM4E | |
| SCHEMBL20070112 | 0.69 | BDKRB2 (0.33) | DPP4KDM4E | |
| SCHEMBL28654985 | 0.68 | CA12 (0.52) | CYP1A2TDP1 | |
| SCHEMBL20069566 | 0.68 | PIK3CD (0.35) | DPP4KDM4E | |
| SCHEMBL18347937 | 0.67 | CYP1A2 (0.34) | CYP1A2TDP1KDM4ECTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071454-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS | ANDREWS STEVEN W (US) | 2018-04-19 | — | — | WO | disclosed |