SCHEMBL20071970

SCHEMBL20071970

Cc1cc2c(cc1C)N(c1ccncc1)C(C1N(c3ccncc3)c3cc(C)c(C)cc3N1c1ccncc1)N2c1ccncc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.34
NCF1 P14598 1/20 0.34
PLD1 Q13393 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
ALDH1A1 P00352 2/20 0.33
POLB P06746 1/20 0.33
CHKA P35790 1/20 0.33
MAPK9 P45984 2/20 0.33
MAPK10 P53779 2/20 0.33
FLT3 P36888 2/20 0.33
MAPK8 P45983 1/20 0.33
GSK3B P49841 1/20 0.33
TDP1 Q9NUW8 2/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
BCHE P06276 1/20 0.32
MAPK14 Q16539 1/20 0.32
ALOX5 P09917 1/20 0.32
NISCH Q9Y2I1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18911912 0.79 RAB9A (0.44) ALDH1A1LMNAMAPTKDM4EHPGD
SCHEMBL18911913 0.79 RAB9A (0.39) L3MBTL1ALDH1A1TDP1LMNAMAPT
SCHEMBL20681860 0.78 CYP2A6 (0.45) L3MBTL1ALDH1A1MAPTNPSR1
SCHEMBL20681874 0.77 LMNA (0.39) ADRB2NCF1PLD1ALDH1A1CHKA
SCHEMBL20681889 0.77 KIF11 (0.43) ALDH1A1POLBTDP1LMNAMAPT
SCHEMBL20071976 0.76 NPC1 (0.41) ALDH1A1POLBLMNAMAPTKDM4E
SCHEMBL20062905 0.73 BCHE (0.42) ADRB2NCF1PLD1L3MBTL1ALDH1A1
SCHEMBL18911915 0.72 HSP90AA1 (0.35) L3MBTL1ALDH1A1POLBLMNAMAPT
SCHEMBL18911919 0.72 ADRB1 (0.31)
SCHEMBL18964694 0.72 CHKA (0.38) ADRB2NCF1PLD1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same CANON KABUSHIKI KAISHA (JP) 2019-01-29 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same BRD1, DRD1, NR2E3 ADRB2 60/4885NCF1 2860/4885PLD1 1368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.