SCHEMBL20071971

SCHEMBL20071971

Cc1cc(N2C(=C3N(c4cc(C)nc(C)c4)c4ccccc4N3c3cc(C)nc(C)c3)N(c3cc(C)nc(C)c3)c3ccccc32)c(C)cn1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.40
CYP2A6 P11509 1/20 0.40
ALDH1A1 P00352 3/20 0.32
KDM4E B2RXH2 2/20 0.32
HPGD P15428 2/20 0.32
HTT P42858 1/20 0.32
NPC1 O15118 1/20 0.31
TP53 P04637 1/20 0.31
LOX P28300 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
LOXL2 Q9Y4K0 1/20 0.31
AHR P35869 1/20 0.31
NCF1 P14598 1/20 0.31
UHRF1 Q96T88 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062910 0.85 CYP1A2 (0.35) CYP1A2CYP2A6ALDH1A1KDM4EHPGD
SCHEMBL19343043 0.74 CYP1A2 (0.53) CYP1A2CYP2A6ALDH1A1NPC1RAB9A
SCHEMBL20681871 0.73 TSHR (0.33) ALDH1A1KDM4EHPGD
SCHEMBL20062913 0.71 GAA (0.36) CYP1A2ALDH1A1KDM4EHPGDHTT
SCHEMBL20062912 0.70 LMNA (0.33) CYP1A2CYP2A6ALDH1A1KDM4EHTT
SCHEMBL18905737 0.67 MAPT (0.45) ALDH1A1HPGDHTTNPSR1
SCHEMBL18905646 0.66 MGLL (0.34) ALDH1A1KDM4EHPGDHTT
SCHEMBL20062907 0.66 ALDH1A1 (0.36) CYP1A2ALDH1A1KDM4EHPGDHTT
SCHEMBL18905756 0.64 NPC1 (0.42) CYP1A2ALDH1A1KDM4EHPGDHTT
SCHEMBL20062915 0.64 HPGD (0.38) ALDH1A1KDM4EHPGDNPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed