SCHEMBL20071978

SCHEMBL20071978

Cc1ccc(N2c3cc(C)c(C)cc3N(c3ccc(C(C)(C)C)cc3)C2C2N(c3ccc(C)cc3)c3cc(C)c(C)cc3N2c2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
HSD11B1 P28845 1/20 0.38
RAB9A P51151 2/20 0.37
NPC1 O15118 2/20 0.37
MAPT P10636 2/20 0.37
NR1H4 Q96RI1 3/20 0.35
NR1I2 O75469 2/20 0.34
GAA P10253 1/20 0.33
CDK8 P49336 1/20 0.32
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
LMNA P02545 2/20 0.31
ALDH1A1 P00352 2/20 0.31
TYR P14679 1/20 0.31
CA9 Q16790 1/20 0.31
RXRA P19793 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18911711 0.89 TSHR (0.48) TSHRHSD11B1RAB9ANPC1MAPT
SCHEMBL18911913 0.88 RAB9A (0.39) RAB9ANPC1MAPTGAAACHE
SCHEMBL18911710 0.84 CYP2D6 (0.35) TSHRNPC1MAPTNR1H4NR1I2
SCHEMBL18911692 0.81 NR1I2 (0.42) TSHRNR1H4NR1I2GAALMNA
SCHEMBL20071827 0.81 KCNH2 (0.36) TSHRNR1H4NR1I2ALDH1A1CA9
SCHEMBL20062869 0.78 TSHR (0.52) TSHRHSD11B1RAB9ANPC1MAPT
SCHEMBL18911896 0.77 ADRB1 (0.36) TSHRHSD11B1MEN1KMT2AALDH1A1
SCHEMBL20071949 0.77 KIF11 (0.41) TSHRMAPTNR1H4SMN1; SMN2ALDH1A1
SCHEMBL18911900 0.77 NR1I2 (0.33) TSHRNR1H4NR1I2LMNAALDH1A1
SCHEMBL20681909 0.74 MAPK13 (0.31) NR1I2CDK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed