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SCHEMBL20072087

SCHEMBL20072087

Cc1ccc2c(c1)N(c1cc(C(C)C)ccc1C(C)C)C(C1N(c3cc(C(C)C)cc(C(C)C)c3)c3cc(C)c(C)cc3N1c1cc(C(C)C)ccc1C(C)C)N2c1cc(C(C)C)cc(C(C)C)c1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ TRPA1 O75762 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ CHRM1 P11229 1/20 0.31
▸ SLC6A2 P23975 1/20 0.31
▸ ADRA1A P35348 1/20 0.31
▸ HTR2B P41595 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18911872 0.83 FAAH (0.33) —
SCHEMBL18911873 0.82 — —
SCHEMBL20072086 0.81 TP53 (0.36) TRPA1LMNA
SCHEMBL18911897 0.79 LMNA (0.31) TRPA1LMNA
SCHEMBL18911894 0.75 LMNA (0.38) TRPA1LMNA
SCHEMBL18911895 0.74 LMNA (0.41) TRPA1LMNA
SCHEMBL18911888 0.71 MGLL (0.39) TRPA1LMNA
SCHEMBL20071764 0.71 MGLL (0.39) TRPA1LMNA
SCHEMBL20071950 0.70 HSD17B10 (0.39) LMNA
SCHEMBL18911903 0.70 NOTUM (0.41) TRPA1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 — — US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 — — US disclosed