SCHEMBL20072086

SCHEMBL20072086

Cc1ccc2c(c1)N(c1ccc(C(C)C)cc1)C(C1N(c3ccc(C(C)C)cc3)c3cc(C)c(C)cc3N1c1ccc(C(C)C)cc1)N2c1ccc(C(C)C)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.36
ALDH1A1 P00352 5/20 0.33
LMNA P02545 4/20 0.33
POLB P06746 3/20 0.33
RECQL P46063 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MGLL Q99685 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
MAPK1 P28482 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
GAA P10253 1/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
MAPT P10636 3/20 0.32
TDP1 Q9NUW8 2/20 0.32
HPGD P15428 1/20 0.32
ALOX12 P18054 1/20 0.32
PKM P14618 1/20 0.32
TRPA1 O75762 1/20 0.32
PTGS1 P23219 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18911888 0.91 MGLL (0.39) TP53ALDH1A1LMNAPOLBRECQL
SCHEMBL20071764 0.84 MGLL (0.39) TP53ALDH1A1LMNAPOLBRECQL
SCHEMBL18911914 0.81 LMNA (0.37) TP53ALDH1A1LMNAPOLBRECQL
SCHEMBL18911710 0.81 CYP2D6 (0.35) ALDH1A1LMNAPOLBRECQLKDM4E
SCHEMBL20072087 0.81 TRPA1 (0.31) LMNATRPA1
SCHEMBL18911895 0.80 LMNA (0.41) ALDH1A1LMNAPOLBRECQLKDM4E
SCHEMBL18911913 0.80 RAB9A (0.39) TP53ALDH1A1LMNAKDM4EMGLL
SCHEMBL18911901 0.78 ABCB1 (0.39) ALDH1A1SMN1; SMN2GAAHPGDPKM
SCHEMBL18911892 0.77 MGLL (0.39) TP53ALDH1A1LMNAPOLBRECQL
SCHEMBL18911905 0.77 CYP2C9 (0.37) ALDH1A1LMNAPOLBRECQLMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed