Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482514 | 0.89 | THRB (0.37) | THRBTSHRALDH1A1TBXAS1POLB | |
| SCHEMBL2484705 | 0.84 | TSHR (0.46) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL1148083 | 0.79 | THRB (0.45) | THRBTSHRALDH1A1TBXAS1POLB | |
| SCHEMBL17589662 | 0.78 | THRB (0.37) | THRBTSHRALDH1A1TBXAS1POLB | |
| SCHEMBL2033134 | 0.78 | THRB (0.40) | THRBTSHRALDH1A1TBXAS1POLB | |
| SCHEMBL13225859 | 0.75 | THRB (0.49) | THRBTSHRALDH1A1TBXAS1POLB | |
| SCHEMBL17285650 | 0.74 | ALDH1A1 (0.35) | ALDH1A1TBXAS1HTTMAPTSMN1; SMN2 | |
| SCHEMBL2577040 | 0.74 | TSHR (0.42) | THRBTSHRADRB2ADRB1ADRB3 | |
| SCHEMBL6808774 | 0.74 | KMT2A (0.41) | ALDH1A1HTTMAPTKMT2A | |
| SCHEMBL27557158 | 0.73 | ALDH1A1 (0.33) | THRBALDH1A1TBXAS1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180105630-A1 | METHOD FOR THE SYNTHESIS OF A COPOLYMER CONTAINING IMIDAZOLE PENDANT GROUPS | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2018-04-19 | — | — | US | disclosed |