Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | WEE1 | P30291 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1148083 | 0.83 | THRB (0.45) | THRBTSHRTDP1POLBAPEX1 | |
| SCHEMBL25507902 | 0.82 | TBXAS1 (0.36) | TDP1WEE1TBXAS1EGLN3AHR | |
| SCHEMBL13225859 | 0.79 | THRB (0.49) | THRBTSHRTDP1POLBAPEX1 | |
| SCHEMBL1783025 | 0.79 | TDP1 (0.38) | TDP1HTTWEE1TBXAS1EGLN3 | |
| SCHEMBL17589662 | 0.79 | THRB (0.37) | THRBTSHRTDP1POLBAPEX1 | |
| SCHEMBL2482514 | 0.78 | THRB (0.37) | THRBTSHRTDP1POLBAPEX1 | |
| SCHEMBL20072386 | 0.78 | THRB (0.36) | THRBTSHRTDP1POLBAPEX1 | |
| SCHEMBL9218688 | 0.78 | TBXAS1 (0.35) | TDP1TBXAS1EGLN3AHRALDH1A1 | |
| SCHEMBL14427880 | 0.76 | TDP1 (0.36) | THRBTDP1TBXAS1EGLN3AHR | |
| SCHEMBL11463256 | 0.76 | EGLN3 (0.45) | TDP1WEE1TBXAS1EGLN3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329486-B2 | Cyanostilbenes | ROLIC AG (CH) | 2019-06-25 | — | — | US | disclosed |
| US-20160083655-A1 | CYANOSTILBENES | ROLIC AG (CH) | 2016-03-24 | — | — | US | disclosed |
| US-7959990-B2 | Adjustment of liquid crystals; oligomers, dendrimers, or polymer in solution is applied to support; crosslinking by radiation or polarized light | ROLIC AG (CH) | 2011-06-14 | — | — | US | disclosed |
| US-20080274304-A1 | Functionalized Photoreactive Compounds | ROLIC AG (CH) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274304-A1 | Functionalized Photoreactive Compounds | PCNA, PIN1, MAP1LC3C | THRB 4831/4885TSHR 4847/4885TDP1 3982/4885 |
| US-20160083655-A1 | CYANOSTILBENES | LATS1, LATS2, CRY1 | THRB 4281/4885TSHR 4718/4885TDP1 1993/4885 |
| US-10329486-B2 | Cyanostilbenes | LATS1, LATS2, CRY1 | THRB 4281/4885TSHR 4718/4885TDP1 1993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.