SCHEMBL1148083

SCHEMBL1148083

C=C(C)C(=O)OCCOC(=O)n1ccnc1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.45
TSHR P16473 3/20 0.40
TDP1 Q9NUW8 2/20 0.35
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TBXAS1 P24557 4/20 0.33
AHR P35869 1/20 0.33
ALDH1A1 P00352 2/20 0.33
CYP24A1 Q07973 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13225859 0.96 THRB (0.49) THRBTSHRTDP1POLBAPEX1
SCHEMBL17589662 0.89 THRB (0.37) THRBTSHRTDP1POLBAPEX1
SCHEMBL12016623 0.87 ALDH1A1 (0.39) TDP1TBXAS1AHRALDH1A1CYP24A1
SCHEMBL9218688 0.85 TBXAS1 (0.35) TDP1TBXAS1AHRALDH1A1CYP1A2
SCHEMBL2033134 0.83 THRB (0.40) THRBTSHRTDP1POLBAPEX1
SCHEMBL10299924 0.82 CYP24A1 (0.36) TSHRTDP1HTTTBXAS1AHR
SCHEMBL27557158 0.82 ALDH1A1 (0.33) THRBHTTTBXAS1AHRALDH1A1
SCHEMBL12467754 0.82 ALDH1A1 (0.36) TSHRTDP1TBXAS1AHRALDH1A1
SCHEMBL12016624 0.82 ALDH1A1 (0.36) TSHRTDP1TBXAS1AHRALDH1A1
SCHEMBL15464597 0.82 ALDH1A1 (0.36) TSHRTDP1TBXAS1AHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11401386-B2 Doubly-crosslinked, emulsion-templated hydrogels through reversible metal coordination TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2022-08-02 US claimed
US-20200148837-A1 DOUBLY-CROSSLINKED, EMULSION-TEMPLATED HYDROGELS THROUGH REVERSIBLE METAL COORDINATION TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2020-05-14 US claimed
WO-2019016816-A9 DOUBLY-CROSSLINKED, EMULSION-TEMPLATED HYDROGELS THROUGH REVERSIBLE METAL COORDINATION TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2019-05-31 WO claimed
WO-2019016816-A1 DOUBLY-CROSSLINKED, EMULSION-TEMPLATED HYDROGELS THROUGH REVERSIBLE METAL COORDINATION TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2019-01-24 WO claimed
US-11401386-B2 Doubly-crosslinked, emulsion-templated hydrogels through reversible metal coordination TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2022-08-02 US disclosed
US-11198748-B2 Resin, resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-12-14 US disclosed
US-10851209-B2 Amphiphilic macromolecules, contact lens thereof and preparing methods thereof NATIONAL CHIAO TUNG UNIVERSITY (TW) 2020-12-01 US disclosed
US-20200148837-A1 DOUBLY-CROSSLINKED, EMULSION-TEMPLATED HYDROGELS THROUGH REVERSIBLE METAL COORDINATION TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2020-05-14 US disclosed
US-20190292287-A1 RESIN, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-09-26 US disclosed
WO-2019016816-A9 DOUBLY-CROSSLINKED, EMULSION-TEMPLATED HYDROGELS THROUGH REVERSIBLE METAL COORDINATION TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2019-05-31 WO disclosed
WO-2019016816-A1 DOUBLY-CROSSLINKED, EMULSION-TEMPLATED HYDROGELS THROUGH REVERSIBLE METAL COORDINATION TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2019-01-24 WO disclosed
US-20170247317-A1 COMPOUNDS, MONOMERS, AND POLYMERS CONTAINING A CARBONATE LINKAGE ISP INVESTMENTS LLC (US) 2017-08-31 US disclosed
US-20150267196-A1 BIODEGRADABLE HYDROGEL FOR POLYNUCLEOTIDE DELIVERY UNIV CASE WESTERN RESERVE (US) 2015-09-24 US disclosed
EP-2067793-B2 Utilization of a wood hydrolysate INNVENTIA AB (SE) 2014-05-21 EP disclosed
US-20130095424-A1 COMPOUND, RESIN AND PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-04-18 US disclosed
US-20130095424-A1 COMPOUND, RESIN AND PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-04-18 US disclosed
US-20110028672-A1 UTILIZATION OF A WOOD HYDROLYSATE INNVENTIA AB (SE) 2011-02-03 US disclosed
EP-2067793-B1 Utilization of a wood hydrolysate INNVENTIA AB (SE) 2010-08-18 EP disclosed
EP-2067793-A1 Utilization of a wood hydrolysate STFI-Packforsk AB (SE) 2009-06-10 EP disclosed
WO-2009068525-A1 UTILIZATION OF A WOOD HYDROLYSATE INNVENTIA AB (SE) 2009-06-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130095424-A1 COMPOUND, RESIN AND PHOTORESIST COMPOSITION C1R, SULT1E1, SULT1A1 THRB 4330/4885TSHR 1841/4885TDP1 4176/4885
US-20170247317-A1 COMPOUNDS, MONOMERS, AND POLYMERS CONTAINING A CARBONATE LINKAGE PARN, CD38, PARG THRB 4758/4885TSHR 4841/4885TDP1 3174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.