SCHEMBL2007499

SCHEMBL2007499

CC(C)COC(=O)COc1ccc(C(=O)CN)cc1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.46
TSHR P16473 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
MAPT P10636 3/20 0.44
HPGD P15428 1/20 0.44
ALDH1A1 P00352 2/20 0.42
LMNA P02545 1/20 0.42
THRB P10828 1/20 0.42
GAA P10253 2/20 0.42
KMT2A Q03164 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2010751 0.84 GAA (0.59) L3MBTL1MAPTHPGDALDH1A1LMNA
Hydrochloric Acid SCHEMBL11660184 0.82 GAA (0.57) L3MBTL1MAPTHPGDALDH1A1LMNA
SCHEMBL2009719 0.82 MAPT (0.60) L3MBTL1MAPTALDH1A1GAAKMT2A
SCHEMBL14198501 0.82 L3MBTL1 (0.48) L3MBTL1TSHRTDP1MAPTLMNA
SCHEMBL2009704 0.82 L3MBTL1 (0.52) L3MBTL1TSHRTDP1MAPTALDH1A1
SCHEMBL2012060 0.80 MAPT (0.53) L3MBTL1MAPTALDH1A1GAAKMT2A
Hydrochloric Acid SCHEMBL11657223 0.79 MAPT (0.51) L3MBTL1MAPTALDH1A1GAAKMT2A
SCHEMBL25079731 0.79 ALDH1A1 (0.52) L3MBTL1TSHRTDP1MAPTHPGD
SCHEMBL19975761 0.79 L3MBTL1 (0.50) L3MBTL1TSHRTDP1MAPTALDH1A1
SCHEMBL10511811 0.79 MAPT (0.54) L3MBTL1TSHRTDP1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7964628-B2 Fibrinogen receptor antagonists and their use PIRAMAL LIFE SCIENCES LIMITED (IN) 2011-06-21 US disclosed
US-20100256161-A1 FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE PIRAMAL LIFE SCIENCES LIMITED (IN) 2010-10-07 US disclosed
US-7759387-B2 Fibrinogen receptor antagonists and their use PIRAMAL LIFE SCIENCES LIMITED (IN) 2010-07-20 US disclosed
US-20070021489-A1 Fibrinogen receptor antagonists and their use NICHOLAS PIRAMAL INDIA LIMITED (IN) 2007-01-25 US disclosed
EP-1677783-A2 FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE Nicholas Piramal India Limited (IN) 2006-07-12 EP disclosed
WO-2005035495-A2 FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE NICHOLAS PIRAMAL INDIA LIMITED (IN) 2005-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256161-A1 FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE FGB, F13B, F2 L3MBTL1 4640/4885TSHR 163/4885TDP1 3983/4885
US-20070021489-A1 Fibrinogen receptor antagonists and their use FGB, F13B, F2 L3MBTL1 4640/4885TSHR 163/4885TDP1 3983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.