SCHEMBL2009704

SCHEMBL2009704

CC(C)COC(=O)COc1ccc(C(=O)CN)cc1OCC(=O)OCC(C)C

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.52
TSHR P16473 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
ITGB3 P05106 3/20 0.46
ITGA2B P08514 3/20 0.46
KMT2A Q03164 2/20 0.45
PDE4B Q07343 1/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 4/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HTT P42858 1/20 0.39
MAPK1 P28482 1/20 0.37
POLB P06746 1/20 0.37
HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2012694 0.85 ALDH1A1 (0.50) L3MBTL1ITGB3ITGA2BKMT2AMEN1
SCHEMBL2007499 0.82 L3MBTL1 (0.46) L3MBTL1TSHRTDP1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL8832741 0.80 KMT2A (0.55) L3MBTL1TSHRITGB3ITGA2BKMT2A
SCHEMBL14427051 0.78 KMT2A (0.44) L3MBTL1TSHRTDP1ITGB3ITGA2B
SCHEMBL2014829 0.78 L3MBTL1 (0.44) L3MBTL1TSHRTDP1ITGB3ITGA2B
Hydrochloric Acid SCHEMBL1725252 0.77 KMT2A (0.43) L3MBTL1TSHRTDP1ITGB3ITGA2B
SCHEMBL8556739 0.77 MEN1 (0.61) L3MBTL1TDP1ITGB3ITGA2BKMT2A
Hydrochloric Acid SCHEMBL8836093 0.77 ALDH1A1 (0.43) L3MBTL1TSHRITGB3ITGA2BKMT2A
SCHEMBL10040757 0.77 ITGB3 (0.54) L3MBTL1TSHRTDP1ITGB3ITGA2B
SCHEMBL17953131 0.76 L3MBTL1 (0.55) L3MBTL1TSHRTDP1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7964628-B2 Fibrinogen receptor antagonists and their use PIRAMAL LIFE SCIENCES LIMITED (IN) 2011-06-21 US disclosed
US-20100256161-A1 FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE PIRAMAL LIFE SCIENCES LIMITED (IN) 2010-10-07 US disclosed
US-7759387-B2 Fibrinogen receptor antagonists and their use PIRAMAL LIFE SCIENCES LIMITED (IN) 2010-07-20 US disclosed
US-20070021489-A1 Fibrinogen receptor antagonists and their use NICHOLAS PIRAMAL INDIA LIMITED (IN) 2007-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256161-A1 FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE FGB, F13B, F2 L3MBTL1 4640/4885TSHR 163/4885TDP1 3983/4885
US-20070021489-A1 Fibrinogen receptor antagonists and their use FGB, F13B, F2 L3MBTL1 4640/4885TSHR 163/4885TDP1 3983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.