Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 15/20 | 0.43 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20075545 | 0.88 | LMNA (0.53) | GRM5SLC34A1LMNANPC1RAB9A | |
| SCHEMBL7973221 | 0.77 | ALDH1A1 (0.51) | GRM5LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL3603486 | 0.76 | GRM5 (0.56) | GRM5SLC34A1LMNANPC1RAB9A | |
| SCHEMBL3595225 | 0.74 | ALDH1A1 (0.49) | GRM5SLC34A1LMNANPC1RAB9A | |
| SCHEMBL16299018 | 0.72 | KDM4E (0.47) | SLC34A1NPC1RAB9AALDH1A1 | |
| SCHEMBL20074997 | 0.71 | ALK (0.36) | LMNANPC1RAB9A | |
| SCHEMBL20075543 | 0.71 | ALDH1A1 (0.48) | GRM5SLC34A1LMNANPC1RAB9A | |
| SCHEMBL20074945 | 0.70 | MAPK14 (0.45) | GRM5LMNAALDH1A1 | |
| SCHEMBL1483023 | 0.69 | KDM2B (0.40) | GRM5NPC1RAB9AALDH1A1 | |
| SCHEMBL4826329 | 0.68 | SLC34A1 (0.55) | SLC34A1LMNANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069222-A1 | SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-04-19 | — | — | WO | disclosed |