Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | RPA1 | P27694 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | HAO2 | Q9NYQ3 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24114810 | 0.86 | NPC1 (0.48) | MAPTNPC1LMNARAB9ATRPM8 | |
| SCHEMBL10172622 | 0.72 | KDM4E (0.56) | MAPTNPC1LMNARAB9ATRPM8 | |
| SCHEMBL20074995 | 0.71 | GRM5 (0.43) | NPC1LMNARAB9A | |
| SCHEMBL10172725 | 0.69 | KDM4E (0.43) | MAPTALPLNPC1RAB9AALOX5 | |
| SCHEMBL20075637 | 0.69 | GABRA2 (0.43) | MAPTNPC1LMNARAB9ATRPM8 | |
| SCHEMBL10172646 | 0.68 | KDM4C (0.51) | MAPTALPLRAB9A | |
| SCHEMBL557321 | 0.67 | MAPT (0.51) | MAPTNPC1LMNARAB9A | |
| SCHEMBL14705878 | 0.66 | GCGR (0.49) | MAPTNPC1LMNARAB9ATRPM8 | |
| SCHEMBL30639631 | 0.65 | MAPK14 (0.47) | ALKMAPTNPC1RAB9AMAPK14 | |
| SCHEMBL4964605 | 0.65 | HAO2 (0.53) | MAPTCA12ALPLRPA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069222-A1 | SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-04-19 | — | — | WO | disclosed |