Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO2 | Q9NYQ3 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | RPA1 | P27694 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570062 | 0.85 | PIN1 (0.47) | HAO2ALPLHCAR2LMNA | |
| SCHEMBL16197762 | 0.84 | ALPL (0.46) | CA12ALPLHCAR2MAPTLMNA | |
| SCHEMBL22637413 | 0.77 | CA12 (0.46) | HAO2CA12ALPLRPA1MAPT | |
| SCHEMBL5255490 | 0.76 | MAPK14 (0.61) | HAO2 | |
| SCHEMBL7646423 | 0.76 | HAO2 (0.49) | HAO2CA12ALPLRPA1 | |
| SCHEMBL27658275 | 0.75 | HAO2 (0.54) | HAO2HCAR2LMNA | |
| SCHEMBL569780 | 0.75 | BRD4 (0.48) | HCAR2 | |
| Water SCHEMBL5256024 | 0.75 | MAPK14 (0.59) | HAO2 | |
| SCHEMBL20074772 | 0.75 | HAO2 (0.42) | HAO2CA12ALPLRPA1HCAR2 | |
| SCHEMBL14705882 | 0.74 | HAO2 (0.44) | HAO2CA12ALPLRPA1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957461-A1 | BISAMIDE INHIBITORS OF HEDGEHOG SIGNALING | Genentech, Inc. (US) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007059157-A1 | BISAMIDE INHIBITORS OF HEDGEHOG SIGNALING | GENENTECH, INC. (US) | 2007-05-24 | — | — | WO | disclosed |