Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769611 | 0.91 | HCAR3 (0.53) | ALDH1A1KDM4EHCAR3NSD2NCOA1 | |
| SCHEMBL7809597 | 0.83 | ALDH1A1 (0.52) | ALDH1A1KDM4EHCAR3NSD2NCOA1 | |
| SCHEMBL29410423 | 0.81 | ALOX15 (0.51) | ALDH1A1KDM4EHCAR3NSD2NCOA1 | |
| SCHEMBL9769601 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KDM4EHCAR3NSD2NCOA1 | |
| SCHEMBL8341967 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EHCAR3NSD2NCOA1 | |
| SCHEMBL871404 | 0.81 | ALOX15 (0.51) | ALDH1A1KDM4EHCAR3NSD2NCOA1 | |
| SCHEMBL28808502 | 0.77 | MAPK1 (0.53) | ALDH1A1HCAR3ALDH3A1TSHRMAPK1 | |
| SCHEMBL3862962 | 0.77 | NSD2 (0.49) | ALDH1A1KDM4EHCAR3NSD2NCOA1 | |
| SCHEMBL4011733 | 0.77 | ALDH1A1 (0.60) | ALDH1A1KDM4EHCAR3NSD2NCOA1 | |
| SCHEMBL1984158 | 0.75 | HSD17B10 (0.51) | ALDH1A1KDM4ENSD2NCOA1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182330-B1 | USE OF 2-NITROANILINE DERIVATIVES AS HAIR DYEING AGENTS, AND 2-NITROANILINE DERIVATIVES | Wella Aktiengesellschaft (DE) | 1991-05-15 | — | — | EP | claimed |
| EP-0182330-A2 | Use of 2-nitroaniline derivatives as hair dyeing agents, and 2-nitroaniline derivatives | Wella Aktiengesellschaft (DE) | 1986-05-28 | — | — | EP | claimed |
| US-11896700-B2 | Process for treating keratin fibers using an anhydrous composition comprising a compound of azomethine type comprising two pyrazolopyridine units and an aqueous composition | L'OREAL (FR) | 2024-02-13 | — | — | US | disclosed |
| US-20230137804-A1 | PROCESS FOR TREATING KERATIN FIBERS USING AN ANHYDROUS COMPOSITION COMPRISING A COMPOUND OF AZOMETHINE TYPE COMPRISING TWO PYRAZOLOPYRIDINE UNITS AND AN AQUEOUS COMPOSITION | L'OREAL (FR) | 2023-05-04 | — | — | US | disclosed |
| EP-1464322-B2 | Use of compositions containing a chosen fluorescent dye and a chosen amphoteric or nonionic surfactant for dyeing human kerateous fibres with a bleaching effect | OREAL (FR) | 2022-06-01 | — | — | EP | disclosed |
| EP-3475278-B1 | (DIS)SYMMETRIC AZOMETHINE-TYPE DIRECT DYE COMPRISING AT LEAST ONE PYRAZOLOPYRIDINE UNIT, PROCESS FOR DYEING KERATIN FIBERS USING THIS DYE | OREAL (FR) | 2021-12-22 | — | — | EP | disclosed |
| US-11000464-B2 | Dyeing composition at acidic pH comprising a direct dye of triarylmethane structure | L'OREAL (FR) | 2021-05-11 | — | — | US | disclosed |
| EP-3393441-B1 | DYEING COMPOSITION COMPRISING A DIRECT DYE OF TRIARYLMETHANE STRUCTURE, AND A SILICONE | OREAL (FR) | 2021-01-20 | — | — | EP | disclosed |
| EP-3474814-B1 | A COMPOUND OF AZOMETHINE TYPE BEARING A QUINOLINE-DERIVED UNIT AND ITS USE FOR DYEING KERATIN FIBERS | OREAL (FR) | 2020-11-11 | — | — | EP | disclosed |
| US-20200268629-A1 | DYEING COMPOSITION AT ACIDIC PH COMPRISING A DIRECT DYE OF TRIARYLMETHANE STRUCTURE | L'OREAL (FR) | 2020-08-27 | — | — | US | disclosed |
| EP-3474814-A1 | USE FOR DYEING KERATIN FIBERS OF A COMPOUND OF AZOMETHINE TYPE BEARING A QUINOLINE-DERIVED UNIT | L'OREAL (FR) | 2019-05-01 | — | — | EP | disclosed |
| EP-1432390-A1 | DYEING COMPOSITION WITH A BRIGHTENING EFFECT FOR HUMAN KERATINOUS FIBRES | L'OREAL (FR) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003028685-A1 | DYEING COMPOSITION WITH A BRIGHTENING EFFECT FOR HUMAN KERATINOUS FIBRES | L'OREAL (FR) | 2003-04-10 | — | — | WO | disclosed |
| WO-2003028684-A2 | COMPOSITION CONTAINING A PYRAZINE DERIVATIVE AND THE USE THEREOF FOR THE DIRECT OR OXIDATION DYEING AND/OR OPTICAL BLEACHING OF KERATIN FIBRES | L'OREAL (FR) | 2003-04-10 | — | — | WO | disclosed |
| WO-1999040894-A1 | USE OF A DIRECT DYEING AGENT DERIVED FROM ALIZARIN FOR DYEING KERATINOUS FIBRES, DYEING COMPOSITIONS CONTAINING SAME AND DYEING METHODS | L'OREAL (FR) | 1999-08-19 | — | — | WO | disclosed |
| WO-1999033436-A1 | USE OF A POLYCYCLIC DIRECT COLOURING AGENT FOR DIRECT OR OXIDATION DYEING OF KERATINOUS FIBRES, DYEING COMPOSITIONS CONTAINING SAME AND DYEING METHODS | L'OREAL (FR) | 1999-07-08 | — | — | WO | disclosed |
| US-5037446-A | 2-nitroaniline derivatives and hair dyeing compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 1991-08-06 | — | — | US | disclosed |
| EP-0182330-B1 | USE OF 2-NITROANILINE DERIVATIVES AS HAIR DYEING AGENTS, AND 2-NITROANILINE DERIVATIVES | Wella Aktiengesellschaft (DE) | 1991-05-15 | — | — | EP | disclosed |
| US-4835314-A | 2-nitroaniline derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 1989-05-30 | — | — | US | disclosed |
| EP-0182330-A2 | Use of 2-nitroaniline derivatives as hair dyeing agents, and 2-nitroaniline derivatives | Wella Aktiengesellschaft (DE) | 1986-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11896700-B2 | Process for treating keratin fibers using an anhydrous composition comprising a compound of azomethine type comprising two pyrazolopyridine units and an aqueous composition | KRT18, DPYD, CKAP4 | ALDH1A1 751/4885KDM4E 801/4885HCAR3 4204/4885 |
| US-11000464-B2 | Dyeing composition at acidic pH comprising a direct dye of triarylmethane structure | KRT18, TYR, DSG1 | ALDH1A1 393/4885KDM4E 1791/4885HCAR3 1210/4885 |
| US-20230137804-A1 | PROCESS FOR TREATING KERATIN FIBERS USING AN ANHYDROUS COMPOSITION COMPRISING A COMPOUND OF AZOMETHINE TYPE COMPRISING TWO PYRAZOLOPYRIDINE UNITS AND AN AQUEOUS COMPOSITION | KRT18, DPYD, CKAP4 | ALDH1A1 751/4885KDM4E 801/4885HCAR3 4204/4885 |
| US-20200268629-A1 | DYEING COMPOSITION AT ACIDIC PH COMPRISING A DIRECT DYE OF TRIARYLMETHANE STRUCTURE | KRT18, TYR, DSG1 | ALDH1A1 393/4885KDM4E 1791/4885HCAR3 1210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.