Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23314136 | 0.77 | — | — | |
| SCHEMBL23314134 | 0.76 | ALDH1A1 (0.43) | CA9 | |
| SCHEMBL24921017 | 0.76 | ALDH1A1 (0.43) | CA9 | |
| SCHEMBL17169692 | 0.73 | LMNA (0.34) | CA12CA9 | |
| SCHEMBL24379420 | 0.68 | CRBN (0.32) | — | |
| SCHEMBL22151320 | 0.62 | IDO1 (0.39) | CA9 | |
| SCHEMBL11390371 | 0.62 | TSHR (0.41) | — | |
| SCHEMBL22692192 | 0.61 | — | — | |
| SCHEMBL23314121 | 0.61 | TSHR (0.42) | CA12CA9 | |
| SCHEMBL24654288 | 0.61 | CRBN (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071606-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | Arvinas, Inc. (US) | 2018-04-19 | — | — | WO | disclosed |