SCHEMBL20076402

SCHEMBL20076402

C=Cc1cc(NC(=C)C2C(c3ccc(F)cc3)C2(C)Cl)cc(C)c1C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20076832 0.77 SLC9A1 (0.43)
SCHEMBL21022010 0.76 MEN1 (0.30) MEN1KMT2A
SCHEMBL20076458 0.75 MEN1 (0.30) MEN1KMT2A
SCHEMBL21021520 0.74
SCHEMBL20076406 0.73 MEN1 (0.30) MEN1LMNAKMT2A
SCHEMBL20076667 0.72 GSTO1 (0.31) MEN1LMNAKMT2A
SCHEMBL21020810 0.71 LMNA (0.36) MEN1LMNAKMT2A
SCHEMBL20076386 0.69 SLC9A1 (0.39)
SCHEMBL21021594 0.68 POLB (0.37) MEN1KMT2A
SCHEMBL20076813 0.67 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018071327-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-04-19 WO disclosed