SCHEMBL20076500

SCHEMBL20076500

C=C(C)c1cc(N)cc(C)c1CC

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.32
NOS2 P35228 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PDE10A Q9Y233 1/20 0.31
ALDH1A1 P00352 2/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20076496 0.80 TBK1 (0.30)
SCHEMBL11412026 0.77 ALDH1A1 (0.43) NOS3NOS2KDM4EMEN1KMT2A
SCHEMBL20076895 0.76 KDM4E (0.39) KDM4EMEN1KMT2ATDP1PDE10A
SCHEMBL20012880 0.70 NOS3 (0.41) NOS3NOS2KDM4EKMT2APDE10A
SCHEMBL1362796 0.69 MAOA (0.37) NOS3NOS2KDM4EMEN1KMT2A
SCHEMBL24146412 0.68 ALDH1A1 (0.50) KDM4EMEN1KMT2APDE10AALDH1A1
SCHEMBL21736856 0.68 NOS3 (0.35) NOS3NOS2KDM4EPDE10AALDH1A1
SCHEMBL21020629 0.68 ALDH1A1 (0.50) KDM4EMEN1KMT2ATDP1PDE10A
SCHEMBL23584500 0.68 PRKCI (0.38) KDM4EMEN1KMT2ATDP1PDE10A
SCHEMBL21984861 0.67 ALDH1A1 (0.39) NOS3NOS2TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018071327-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-04-19 WO disclosed