SCHEMBL20076704

SCHEMBL20076704

C=C(C(F)=C(C)C)c1cc(NCC)ccc1C

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
RECQL P46063 1/20 0.35
HTT P42858 1/20 0.33
LCK P06239 1/20 0.32
BTK Q06187 1/20 0.32
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28076217 0.75 CYP3A4 (0.39) ALDH1A1CYP3A4TSHRRECQLHTT
SCHEMBL22818562 0.68 ALDH1A1 (0.41) ALDH1A1CYP3A4HTTMAPT
SCHEMBL23484214 0.68 MAPT (0.38) ALDH1A1CYP3A4TSHRRECQLHTT
SCHEMBL30536438 0.67 ALDH1A1 (0.55) ALDH1A1CYP3A4TSHRRECQLHTT
SCHEMBL1803111 0.67 ALDH1A1 (0.55) ALDH1A1CYP3A4TSHRRECQLHTT
SCHEMBL1800645 0.67 KMT2A (0.50) ALDH1A1CYP3A4TSHRRECQLHTT
SCHEMBL3962037 0.67 ALDH1A1 (0.54) ALDH1A1CYP3A4TSHRRECQLADRA2A
SCHEMBL24074262 0.66 ALDH1A1 (0.46) ALDH1A1HTTMAPT
SCHEMBL1485822 0.64 RECQL (0.62) ALDH1A1CYP3A4TSHRRECQLHTT
SCHEMBL13037977 0.64 HTT (0.40) ALDH1A1CYP3A4TSHRRECQLHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018071327-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-04-19 WO disclosed