SCHEMBL28076217

SCHEMBL28076217

C=C(NCC)c1cc(NCC)ccc1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.39
RECQL P46063 2/20 0.39
TSHR P16473 2/20 0.39
ALDH1A1 P00352 3/20 0.36
HTT P42858 1/20 0.36
ADRA2A P08913 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
MAPT P10636 4/20 0.33
CASR P41180 1/20 0.33
KDM4C Q9H3R0 1/20 0.33
NPC1 O15118 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
RAB9A P51151 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
LCK P06239 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20076704 0.75 ALDH1A1 (0.36) CYP3A4RECQLTSHRALDH1A1HTT
SCHEMBL20865394 0.73 MAOA (0.49) RECQLALDH1A1HTTMAPTNPC1
SCHEMBL1803111 0.72 ALDH1A1 (0.55) CYP3A4RECQLTSHRALDH1A1HTT
SCHEMBL30536438 0.72 ALDH1A1 (0.55) CYP3A4RECQLTSHRALDH1A1HTT
SCHEMBL26039684 0.71 SKP2 (0.36) CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL3962037 0.71 ALDH1A1 (0.54) CYP3A4RECQLTSHRALDH1A1ADRA2A
SCHEMBL20156979 0.69 CACNA1C (0.33) HPGD
SCHEMBL23484214 0.69 MAPT (0.38) CYP3A4RECQLTSHRALDH1A1HTT
SCHEMBL9172326 0.69 RECQL (0.47) CYP3A4RECQLTSHRALDH1A1HTT
SCHEMBL1485822 0.69 RECQL (0.62) CYP3A4RECQLTSHRALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105658760-A Well treatment fluids containing a zirconium crosslinker and methods of using the same 贝克休斯公司 2016-06-08 CN disclosed