Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | BMX | P51813 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24022917 | 0.81 | ALDH1A1 (0.36) | ALDH1A1LMNATHRBNPSR1DHODH | |
| SCHEMBL20076366 | 0.76 | LMNA (0.31) | ALDH1A1LMNATHRBNPSR1KDM4E | |
| SCHEMBL20076738 | 0.74 | DHODH (0.32) | ALDH1A1LMNATHRBNPSR1DHODH | |
| SCHEMBL20076783 | 0.73 | KDM4E (0.37) | ALDH1A1LMNATHRBNPSR1KDM4E | |
| SCHEMBL20076380 | 0.72 | MEN1 (0.35) | ALDH1A1LMNATHRBNPSR1DHODH | |
| SCHEMBL20076509 | 0.72 | KDM4E (0.36) | ALDH1A1LMNATHRBNPSR1KDM4E | |
| SCHEMBL20077004 | 0.72 | KDM4E (0.36) | ALDH1A1LMNATHRBNPSR1DHODH | |
| SCHEMBL20076762 | 0.71 | NPC1 (0.30) | RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL20076362 | 0.71 | BRAF (0.32) | BRAFMEN1KMT2AMAPK1TSHR | |
| SCHEMBL20076423 | 0.70 | KDM4E (0.41) | ALDH1A1LMNATHRBNPSR1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071327-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2018-04-19 | — | — | WO | disclosed |