Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20076738 | 0.89 | DHODH (0.32) | KDM4ERAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL20076783 | 0.83 | KDM4E (0.37) | KDM4ERAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL20076509 | 0.82 | KDM4E (0.36) | KDM4ERAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL20076423 | 0.80 | KDM4E (0.41) | KDM4EPDK1PDK2PDK3PDK4 | |
| SCHEMBL21019686 | 0.79 | RAB9A (0.42) | KDM4EPDK1PDK2PDK3PDK4 | |
| SCHEMBL20076766 | 0.77 | KDM4E (0.41) | KDM4ERAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL21020713 | 0.74 | PTGS2 (0.41) | KDM4ERAB9ASMN1; SMN2MAPTPPARG | |
| SCHEMBL21021625 | 0.73 | RAB9A (0.41) | KDM4ERAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL21021523 | 0.72 | RAB9A (0.40) | KDM4EPDK1PDK2PDK3PDK4 | |
| SCHEMBL24022917 | 0.72 | ALDH1A1 (0.36) | KDM4ERAB9ASMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071327-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2018-04-19 | — | — | WO | disclosed |