Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20078126 | 0.85 | LMNA (0.45) | LMNATSHRL3MBTL1PIK3CBPKM | |
| SCHEMBL8537283 | 0.81 | LMNA (0.61) | LMNATSHRL3MBTL1MAPTPKM | |
| SCHEMBL8535478 | 0.74 | SMN1; SMN2 (0.61) | LMNATSHRL3MBTL1MAPTPKM | |
| SCHEMBL12490124 | 0.69 | SMN1; SMN2 (0.63) | LMNATSHRL3MBTL1MAPTALDH1A1 | |
| SCHEMBL1308905 | 0.68 | MAPT (0.61) | LMNAL3MBTL1MAPTPOLBALDH1A1 | |
| SCHEMBL38827 | 0.68 | MAPT (0.57) | LMNAL3MBTL1MAPTPOLBALDH1A1 | |
| SCHEMBL3500290 | 0.66 | LMNA (0.61) | LMNAMAPTPKMPOLBHTT | |
| SCHEMBL27776226 | 0.65 | LMNA (0.81) | LMNAMAPTPOLBNPSR1HTT | |
| SCHEMBL8342797 | 0.64 | ALDH1A1 (0.55) | LMNATSHRL3MBTL1PKMPOLB | |
| SCHEMBL18383753 | 0.64 | MAPT (0.51) | L3MBTL1MAPTPKMALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951040-B2 | 1,3,5 -triazine based PI3K inhibitors as anticancer agents and a process for the preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2018-04-24 | — | — | US | disclosed |