Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | GAA | P10253 | 5/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 7/20 | 0.34 |
| ▸ | NPC1 | O15118 | 6/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.34 |
| ▸ | RELA | Q04206 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3267635 | 0.84 | MEN1 (0.41) | MAPTALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL17342821 | 0.84 | APLNR (0.33) | APLNR | |
| SCHEMBL16489114 | 0.79 | CA12 (0.36) | MAPTALDH1A1GAAMAPK1HTT | |
| SCHEMBL12118354 | 0.79 | MAPT (0.35) | MAPTALDH1A1GAAHTTRAB9A | |
| SCHEMBL9000066 | 0.78 | SMN1; SMN2 (0.40) | MAPTALDH1A1GAAKDM4ERAB9A | |
| SCHEMBL18760512 | 0.78 | RAB9A (0.36) | MAPTALDH1A1RAB9ANPC1L3MBTL1 | |
| SCHEMBL12515075 | 0.77 | CA1 (0.34) | ALDH1A1KDM4C | |
| SCHEMBL12093970 | 0.75 | ALDH1A1 (0.36) | MAPTALDH1A1MAPK1KDM4ERAB9A | |
| SCHEMBL7120029 | 0.74 | SMN1; SMN2 (0.39) | MAPTALDH1A1GAAKDM4ERAB9A | |
| SCHEMBL14039656 | 0.74 | ALDH1A1 (0.35) | MAPTALDH1A1GAAKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951085-B2 | Labeled chemically reactive and biologically active comjugates, and methods and compositions thereof | SUN YI (US) | 2018-04-24 | — | — | US | disclosed |