Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.67 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18233617 | 0.88 | APLNR (0.71) | APLNRHTR2AHTR2CDPP7MEN1 | |
| SCHEMBL7768853 | 0.85 | APLNR (0.86) | APLNRHTR2AHTR2CDPP7MEN1 | |
| SCHEMBL783785 | 0.81 | APLNR (1.00) | APLNRHTR2AHTR2CMEN1KMT2A | |
| SCHEMBL29987676 | 0.81 | APLNR (0.63) | APLNRHTR2AHTR2CDPP7MEN1 | |
| SCHEMBL18256578 | 0.80 | APLNR (0.77) | APLNRHTR2AHTR2CDPP7MEN1 | |
| SCHEMBL22048877 | 0.79 | APLNR (0.65) | APLNRHTR2AHTR2CTSHR | |
| SCHEMBL31114343 | 0.79 | APLNR (0.75) | APLNRHTR2AHTR2CDPP7MEN1 | |
| SCHEMBL14971128 | 0.79 | APLNR (0.75) | APLNRHTR2AHTR2CDPP7MEN1 | |
| SCHEMBL29580030 | 0.79 | APLNR (0.75) | APLNRHTR2AHTR2CDPP7MEN1 | |
| SCHEMBL16735971 | 0.79 | APLNR (0.60) | APLNRHTR2AHTR2CDPP7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951065-B2 | Benzimidazole and imadazopyridine carboximidamide compounds | GILEAD SCIENCES, INC. (US) | 2018-04-24 | — | — | US | disclosed |